Embedded in the Harvard Medical School campus, Systems Biology Department researchers have access to a wide range of core facilities. The Department manages three facilities:
Systems Biology Microscopy Facility (SBMF) is a core facility for light microscopy developed in partnership with Nikon Instruments Inc. and Micro Video Instruments Inc. The SBMF maintains laser scanning confocals, spinning disk confocals, a total internal fluorescence system, and other basic fluorescence and transmitted light microscopes. All users are offered training to use the equipment; no prior imaging experience is necessary. Director: Dr. Jennifer Waters.
Systems Biology FACS Facility - The Systems Biology FACS facility houses two state-of-the-art BD analyzers with high-throughput capability, a high-speed BD cell sorter with an automatic plate deposition unit, and both Mac and PC workstations for data analysis. Sorting services are offered through the facility, as well as instrument and software training. Instruments include a BD FACSCalibur (488nm/635nm; 4-color), BD SORP LSRII with HTS (405nm/488nm/594nm; 12-color), and a BD FACSAria IIu (405nm/488nm/633nm; 9-color). Data analysis software available at the facility includes ModFit, FlowJo, Diva 6.1.2, and CellQuestPro. Director: Dr. Jodi Moore.
HMS Microfluidics Facility - The HMS Microfluidics Facility aims to make the tools of microfabrication and microfluidics available to all HMS users. Microfluidics has the potential to do for biology what microprocessors have done for computational sciences by integrating complex chemical and biological processes into one chip, facilitating the study of complex biological systems. Manager: Calixto Saenz.