Martin Loose Ph.D.

Fax:
617-432-5012

address

Department of Systems Biology
200 Longwood Avenue
Warren Alpert Building
Boston, MA 02115

Bio

Dr. Loose's  research goal is to investigate the mechanisms of biochemical self-organization. He is particularly interested in how minimal protein systems are able to organize intracellular space and how these biochemical modules are conserved or change during evolution. For this he mainly uses biochemical approaches and microscopic techniques.

 

Select Publications:

Schweizer, J., Loose, M., Bonny, M., Kruse, K., Mönch, I. & Schwille, P..
(2012).
Geometry sensing by self-organized protein patterns.
Proc Natl Acad Sci U S A..
epub ahead of print,
PMID:
Loose, M. , Kruse, K. & Schwille, P..
(2011).
Protein self-organization: lessons from the min system .
Annual Review of Biophysics.
40,
315-36
PMID:
Loose, M. , Fischer-Friedrich, E., Herold, C., Kruse, K. & Schwille, P..
(2011).
Min protein patterns emerge from rapid rebinding and membrane interaction of MinE .
Nature Structural & Molecular Biology.
577-83
PMID:
Loose, M. & Schwille, P..
(2009).
Biomimetic membrane systems to study cellular organization.
Journal of Structural Biology.
168(1),
143-51
PMID:
Dinarina, A., Pugieux, C., Corral, M.M., Loose, M., Spatz, J., Karsenti, E. & Nédélec, F..
(2009).
Chromatin shapes the mitotic spindle.
Cell.
138(3),
502-13
PMID:
Loose, M. , Fischer-Friedrich, E., Ries, J., Kruse, K. & Schwille, P..
(2008).
Spatial regulators for bacterial cell division self-organize into surface waves in vitro.
Science.
320(5877),
789-92
PMID: