Seminar

2018 Oct 30

Seminar: Sudipta Ashe

11:00am to 12:00pm

Location: 

WAB 563

TitleProtein Kinase D regulates secretion of Drosophila Insulin through a Stunted dependent Inter-organ communication from the fatbody

AbstractGrowth and development of metazoan body plan requires a coordinated processes of cell division, migration and differentiation. These processes are regulated at level of gene transcription, translation, post...

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2018 Aug 17

One Last Thing Before I Go: Kyogo Kawaguchi

2:00pm to 3:00pm

Location: 

WAB 563

Systems Biology Post Docs' final departmental talk before they move on.

Title: Fate coordination and collective migration: Statphys of multicellular dynamics

2018 Nov 08

Seminar: Ute Deichmann

2:00pm to 3:00pm

Location: 

WAB 563

Jacques Loeb Centre for the History and Philosophy of the Life Sciences
Ben-Gurion University of the Negev, Israel

Title: Biological specificity, genetic causation, and mathematical modelling in the history of modern biology

Abstract: The concepts of biological specificity (of species, macromolecules, genes etc.) and genetic causality (in particular regarding heredity and development) played an important role in rendering biology a modern experimental science in the nineteenth century. Neglecting these concepts often...

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2018 Oct 16

Seminar: Ruth Williams

2:30pm to 3:30pm

Location: 

WAB 563

Department of Mathematics
UC San Diego

Title: Correlations and adaptation in enzymatic networks

Abstract: The contrast between stochasticity of biochemical networks and regularity of cellular behavior suggests that biological networks generate robust behavior from noisy constituents. Identifying the mechanisms that confer this ability on biological networks is essential to understanding cells. Here we use stochastic queueing models to investigate one potential mechanism. In living cells, enzymes perform the critical function of...

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2018 Jul 13

Seminar: Chirlmin Joo

11:00am to 12:00pm

Location: 

WAB 563

Kavli Institute of NanoScience and Department of BioNanoScience
Delft University of Technology, Delft, The Netherlands

Title: Fast and accurate target recognition by small RNAs

 

2018 Jul 06

Seminar: Joshua François

10:00am to 12:00pm

Location: 

WAB 436

Bioengineering Department
University of California, San Diego

Title: Investigating the effect of matrix density on the kinematics and mechanics of neutrophil migration in three-dimensional extracellular matrices

2018 Aug 02

Seminar: Alan Rendall

2:00pm to 3:00pm

Location: 

WAB 436

Title: Models for the initiation of T cell activation

Abstract: This talk is concerned with mathematical models describing events during the first few minutes after the encounter of a naive mature T cell with its antigen. I will describe results obtained with Eduardo Sontag showing that some of these models exhibit behaviour which had not previously been noticed such as multiple steady states and damped oscillations. In addition I will discuss features of the response function which are predicted by this type of...

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2018 Mar 26

Seminar: Manoj Gopalkrishnan

2:00pm to 3:00pm

Location: 

WAB 563
Department of Electrical Engineering
Indian Institute of Technology Bombay

Department of Electrical Engineering
Indian Institute of Technology Bombay

Title: Imagining how a cell thinks: The design of reaction network schemes that do machine learning

Abstract: A living cell responds in sophisticated ways to its environment. Such behavior is all the more remarkable when one considers that a cell is a bag of molecules. A detailed algorithmic explanation is required for how a network of chemical reactions...

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2018 Jan 23

Seminar: Mogens Høgh Jensen

1:00pm to 2:30pm

Location: 

WAB 563

Title: Couples Oscillations in Biology

Abstract: The control of proteins by a transcription factor with periodically varying concentration exhibits intriguing dynamical behavior. If the concentration of another element, for instance a ligand responsible for the activation of the transcription factor, is oscillating as well, the system of coupled oscillators can create regions of bistable oscillation states. We investigate how transitions between different entrained states caused by intrinsic noise affect the expression of downstream...

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2017 Nov 28

Seminar: Carl Pabo

2:00pm

Location: 

Warren Alpert 563

Title: Human Thought and the Human Future:  A Structural Biologist Offers New Approaches for Solving World Problems ​​​​

Bio: Carl Pabo spent several decades doing research on the structure and design of DNA-binding proteins, making some fundamental contributions to the field.  In 2001, he decided to leave his positions as a tenured professor at MIT and an investigator at the Howard Hughes Medical Institute to look at some even-more-critical questions about the power and limits of human thought....

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2017 Dec 12

Seminar: Neil Kelleher

11:00am to 12:00pm

Location: 

WAB 563

Title: When good isoforms go bad: Mapping mutation/modification cross talk on KRAS4b in colorectal cancer

Neil Kelleher
Department of Chemistry, Weinberg College of Arts & Sciences
Northwestern University
 
Abstract: Oncogenic mutations of KRAS are found in ~22% of human cancers and result in constitutive activation of downstream...
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