• We use the tools of mathematics and computation

    Biology is too complicated for the unaided human brain!

  • Location, Location, Location

    We're located in the heart of the Longwood Medical Area, one of the greatest concentrations of biomedical science in the world.

  • Measure twice. Model once.

    Quantitative measurements are essential to build and test worthwhile models.

  • retreat photo hands up

    Systems Biology Retreat in Beautiful Maine!

    Our 2019 department retreat was held at Sebasco Harbor in Maine.

Welcome to the Department of Systems Biology

Systems biology is the study of systems of biological components, which may be molecules, cells, organisms or entire species. Living systems are dynamic and complex, and their behavior may be hard to predict from the properties of individual parts. To study them, we use quantitative measurements of the behavior of groups of interacting components, systematic measurement technologies such as genomics, bioinformatics and proteomics, and mathematical and computational models to describe and predict dynamical behavior. Systems problems are emerging as central to all areas of biology and medicine.

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Upcoming Events

2019 Sep 27

Theory Lunch: Torbjorn Lundh

12:00pm to 2:00pm


Warren Alpert Building 563

Torbjorn Lundh - Why don't circular wounds heal and a few other bloody problems?


The father of all physicians, Hippocrates, is believed to have stated the following question: Why do not circular wounds heal? Later, in Posterior Analytics I, Aristotle picked up Hippocrates' finding and moderated the statement somewhat: "It belongs to the physician to know that circular wounds heal more slowly, but it belongs to the geometer to...

Read more about Theory Lunch: Torbjorn Lundh
2019 Oct 01

Pizza Talk- Suhyun Kim

12:30pm to 1:30pm


Warren Alpert Building 563
"Engineering therapeutic bacteria against food poisoning using synthetic biology" Read more about Pizza Talk- Suhyun Kim
2019 Oct 04

Theory Lunch: Lea Goentoro

12:00pm to 2:00pm


Warren Alpert Building 563

Lea Goentoro - Why are jellyfish round?


Standing on a British shore a century ago, D'Arcy Thompson wondered whether the shape of a medusa can be likened to the equilibrium form of a gelatinous drop. While many study how animals get their shapes during development, less is understood about how or whether animal shape is regulated in adulthood. We pursue this question of animal shape regulation in the moon jellyfish, Aurelia aurita....

Read more about Theory Lunch: Lea Goentoro