• A researcher studies data on two monitors

    We use the tools of mathematics and computation

    Biology is too complicated for the unaided human brain!

  • An aerial view of the Harvard Medical School campus

    Location, Location, Location

    We're located in the heart of the Longwood Medical Area, one of the greatest concentrations of biomedical science in the world.

  • A female researcher handling vials in a lab

    Measure twice. Model once.

    Quantitative measurements are essential to build and test worthwhile models.

  • A group shot of all department members outdoors by a lake

    Systems Biology Retreat in Beautiful Maine!

    Our 2019 department retreat was held at Sebasco Harbor in Maine.

Welcome to the Department of Systems Biology

Our department aims to identify the quantitative principles that govern complex interactions across all areas of biology and medicine. Our goal is to develop a conceptual and predictive understanding of the living world, to enable the design and control of biological systems and the advancement of human health and welfare.



Trying to manage curiosity-driven science risks limiting discoveries

March 16, 2021

Ever since Arthur D. Little created the first consulting firm in 1886, management consultants have turned their attention to nearly everything from advertising to education to statecraft. They and their management principles are now insinuating themselves into the funding, management, and training of scientists. We think that threatens scientific discovery at its very core....


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