Faculty Research Areas
Our faculty take a quantitative and mathematical approach to problems of complex intracellular and intercellular circuits, phenotypic variation and evolution. Almost all labs in the Department integrate experiment and theory, sometimes in a collaboration within or across labs, and sometimes within a single person.
Areas of special interest include:
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Developmental Biology
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Disease/Therapeutics/Pharmacology
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Mathematical And Computational Biology
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Signaling and Cellular Decision-Making
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Organization of Cells and Organisms in Time and Space
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Synthetic Biology
Synthetic Biology Hive
Solutions invented by life on earth
Hive Intro Video
Featured Videos
Science Matters -
Galit Lahav: The aha! moment
Galit Lahav
Science Matters -
Jeremy Gunawardena: DNA is Dead!
Jeremy Gunawardena
Science Matters -
Angela DePace: Loving life in the lab
Angela DePace
'Lifespan Machine' Probes Cause of Aging
The Fontana Lab
Fontana Lab
Zebrafish embryonic development at single cell resolution
The Megason Lab
This movie provides a single-cell resolution top view of a developing zebrafish embryo from 2-cell stage to 24 hours post fertilization (hpf). Movie is a continous sequence of 700 images with time stamp (unit:hours and minutes post fertilization) at 7 frame/second. Each image is a 3D projection of a Z-stack (210μm deep) of confocal slices (600μm in height and width), taken with confocal microscope (Objective: 20X) at 2 minute time intervals continuously. Cell membranes were labeled with membrane targeted yellow fluorescent protein (colored cyan in the movie) and cell nucleus with histone2B tagged red fluorescent protein (colored yellow in the movie). This movie allows researchers to follow the cell divisions and movements, as well as changes of cell shapes, in a systematic fashion.
Megason Lab
Discrete Molecular Imaging by the Wyss Institute
The Wyss Institute
Wyss Institute